- Extant genomes: BOREO_PERM_200_u.txt
- Ancestral syntenies.
- Format: Each line of a file represents an ancestral synteny: the first
field is the weight of this synteny and the remaining fields are the labels of
the synteny blocks that define it.
- All ancestral syntenies (non-conflicting adjacencies and maximum common
intervals) detected during the first step of our method and used to compute the
generalized PQ-tree:
BOREO_ANCESTRAL_SYNTENIES_200_u.txt.
- Ancestral syntenies that were not discarded to remove ambiguities and are
used to compute the PQ-tree:
BOREO_PQ_SYNTENIES_200_u.txt.
- Genome architectures: PQ-trees.
- Format:
The P, Q and R nodes of a tree are indicated as follows: _P (resp. _Q, _R)
indicates the beginning of a P (resp. Q, R) node and P_ (resp. Q_, R_)
indicates the end of a P (resp. Q, R) node. The integers represent synteny
block labels.
- Generalized PQ-tree representing all ancestral syntenies:
BOREO_GPQ_200_u.txt.
- PQ-tree representing unambiguous ancestral genome architectures:
BOREO_PQ_200_u.txt.
- Conserved segements (segments of synteny blocks that are colinear in the
ancestor and in the human genome).
- Format:
Each line represents a conserved segment. The first field is the label of the
conserved sement. The remaining fields are the synteny blocks that define this
conserved segment.
- List of conserved segments
BOREO_CS_200_u.txt.
- PQ-tree of these conserved segments
BOREO_PQ_CS_200_u.txt
- Chromosomal syntenies between the inferred CARs and the 6 ingroup genomes.
- Format: XX (YY) indicates that synteny block of label YY of the chromosome
XX belong to a given CAR.
- Generalized PQ-tree
BOREO_GPQ_CHR_SYNTENIES_200_u.txt.
- PQ-tree
BOREO_PQ_CHR_SYNTENIES_200_u.txt.
- Support of adjacencies.
- Format: Each line represents an adjacency that is present in all ancestral
genome architectures defined by the PQ-tree. The first field is the weight of
his adjacency (according to the weighting formula used in the paper). The two
following fields are the two synteny blocks that define the adjacency. The
fourth field is the number of ancestral syntenies that contain these two
synteny blocks. The fifth field is the cumulated weight of these ancestral
syntenies. The last field is the average weight of these syntenies.
- List of adjacencies and of their support
BOREO_SUPP_ADJ_200_u.txt.
- Results using Ma et al. method
Reconstructing
contiguous regions of an ancestral genome.
- Input files.
- Coordinates of synteny blocks. The coordinates we use are not
the real coordinates, but respect the chromosome locations and relative
position and orientation of synteny blocks in our data. Moreover, the synteny
blocks have been relabelled in order that they have consecutive numbers, which
was required by the program.
BOREO_SUPP_MA_COORDS_200_u.txt.
- Config file.
BOREO_SUPP_MA_CONFIG_200_u.txt.
- Results generated by the command
createGenomeFile BOREO_SUPP_MA_CONFIG_200_u.txt
BOREO_SUPP_MA_COORDS_200_u.txt > BOREO_SUPP_MA_PERM_200_u.txt
Genome file: BOREO_SUPP_MA_PERM_200_u.txt
Joins files:
hg18.joins,
rheMac2.joins,
mm9.joins,
rn4.joins,
bosTau3.joins,
canFam2.joins,
monDom4.joins,
galgal3.joins.
- Results generated by the command
inferCars BOREO_SUPP_MA_CONFIG_200_u.txt BOREO_SUPP_MA_PERM_200_u.txt
Joins in the ancestor Ancestor.joins and
CARs Ancestor.car.
- Chromosomal syntenies between the inferred CARs and the 6 ingroup genomes:
BOREO_MA_CHR_SYNTENIES_200_u.txt.
- Support of adjacencies: BOREO_SUPP_MA_ADJ_200_u.txt